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Product details
Cat#：163P02
Three Letter Code: H-Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH trifluoroacetate salt
One Letter Code: MAPRGFSCLLLLTSEIDLPVKRRA
Molecular Formula: C₁₁₉H₂₀₄N₃₄O₃₂S₂
Relative Molecular Mass: 2687.27
CAS#: 330936-69-1
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Alzheimer´s Disease
Details: Humanin (HN) is a polypeptide suppressing neuronal cell death induced by several familial Alzheimer´s disease genes and by amyloid β-protein (1-43) (human). It has been shown that amyloid β-protein (1-40) and amyloid β-protein (1-42) secretion is not affected by humanin in F11 cells expressing the familial Alzheimer´s disease gene K595N/M596L-APP. Inhibitory actions on neuronal cell death triggered by K595N/M596L-APP directly and caused by amyloid β-protein have been suggested.
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