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Product details
Cat#:166P04
Three Letter Code: Ac-Arg-Arg-Trp-Trp-Cys-Arg-NH₂ trifluoroacetate salt
One Letter Code: Ac-RRWWCR-NH₂
Synonyms: Antileukinate
Molecular Formula: C₄₅H₆₆N₁₈O₇S
Relative Molecular Mass: 1003.2
CAS#: 138559-60-1
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cytokines/Chemokines & their Receptors
Details: Antileukinate, Ac-RRWWCR-amide, inhibits the specific binding of ¹²⁵I-labeled IL-8 to neutrophils with an apparent Ki = 10 µM. The hexapeptide also significantly suppresses neutrophil chemotaxis induced by 10 nM IL-8 at a concentration of 50 µM. The inhibition is specific for IL-8.
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