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Product details
Cat#:166P06
Three Letter Code: Ac-Met-Trp-Asp-Phe-Asp-Asp-Leu-Asn-Phe-Thr-Gly-Met-Pro-Pro-Ala-Asp-Glu-Asp-Tyr-Ser-Pro-NH₂
One Letter Code: Ac-MWDFDDLNFTGMPPADEDYSP-NH₂
Synonyms: Interleukin-8 receptor antagonist (9-29)
Molecular Formula: C₁₁₂H₁₅₀N₂₄O₃₈S₂
Relative Molecular Mass: 2504.69
CAS#: 188689-66-9
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cytokines/Chemokines & their Receptors
Details: Acetyl-MWDFDDLNFTGMPPADEDYSP-amide, a peptide derived from a single extracellular subdomain of the IL-8 receptor was shown to be a potent inhibitor of the IL-8/IL-8 receptor interaction. It inhibited IL-8 binding with Ki = 13 µM. This peptide was also highly selective for IL-8 over C5a.
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