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Product details
Cat#：167P01
Three Letter Code: H-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ trifluoroacetate salt
One Letter Code: LPNYNWNSFGLRF-NH₂
Synonyms: Malignant Melanoma Metastasis-Suppressor KiSS-1 (109-121) (human), KiSS-1 (109-121) (human), Metastin (42-54) (human), Kisspeptin-14 (2-14) (human), Kisspeptin-54 (42-54) (human)
Molecular Formula: C₇₈H₁₀₇N₂₁O₁₈
Relative Molecular Mass: 1626.84
CAS#: 374675-18-0
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cancer Research
Details: An LRF-amide motif containing fragment of malignant melanoma metastasis suppressor KiSS-1. It bound with low nanomolar affinity to the rat and human G protein-coupled receptor GPR54 expressed in Chinese hamster ovary K1 cells and stimulated PIP₂ hydrolysis, Ca²⁺ mobilization, arachidonic acid release, ERK1/2 and p38 MAP kinase phosphorylation, and stress fiber formation but inhibited cell proliferation.
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