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Product details
Cat#：173P25
Three Letter Code: 6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH₂ trifluoroacetate salt
One Letter Code: NBD-ε-aminocaproyl-RPKPLA-Nva-WK(DMACA)-NH₂
Synonyms: NBD-ε-aminocaproyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMACA)-NH₂
Molecular Formula: C₇₈H₁₁₁N₂₁O₁₆
Relative Molecular Mass: 1598.87
CAS#: 945414-97-1
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cancer Research|
Inflammation Research
Details: NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMC)-NH₂ (NBD-RPKPLA-Nva-WK(DMC) amide) is an excellent fluorogenic substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3). This FRET substrate exhibits high sensitivity and improves accuracy at lower substrate turnover. It has a kcat/Km value of 2.14 x 10⁴ M⁻¹s⁻¹ and can be easily detected at 350 nm (excitation) and 465 nm (emission). Therefore this compound is a suitable tool for high-throughput inhibitor screening.
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