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/Melanocyte-Stimulating Hormone (MSH) (30)
/Acetyl-(D-Arg¹⁰,Cys¹¹,D-Phe¹⁴,Cys¹⁷)-β-MSH (10-17) amide trifluoroacetate salt
Product details
Cat#：174P21
Three Letter Code: Ac-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH₂ trifluoroacetate salt(Disulfide bond)
One Letter Code: Ac-rCEHfRWC-NH₂
Molecular Formula: C₅₁H₇₀N₁₈O₁₁S₂
Relative Molecular Mass: 1175.36
CAS#: 819048-44-7
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Obesity Research|
Pituitary & Hypothalamic Hormones
Details: Highly potent and selective β-MSH-derived melanocortin-4 receptor (MC-4R) agonist with sub-nanomolar potency. The binding affinities for human MC-4R, MC-1R, MC-3R and MC-5R were 0.55 ± 0.06, 16.78 ± 1.53, 56.79 ± 4.66, and < 500 nM, respectively. Daily subcutaneous injection of this product to diet-induced obese rats over a period of 14 days demonstrated an effect on reduction of fat mass.
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