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Product details
Cat#：186P35
Three Letter Code: H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide · HCl
One Letter Code: Y-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide · HCl
Synonyms: H-Tyr-Tic-NH₂ · HCl
Molecular Formula: C₁₉H₂₁N₃O₃ · HCl
Relative Molecular Mass: 375.86
CAS#: 154121-70-7
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Di- and Tripeptides
Details: Tyr-Tic-amide and its epimer are the first example for opioid peptides consisting of a message domain of only two residues. In addition, they are the first opioid dipeptides with significant opioid activity and represent a first meaningful link among peptide opioids and alkaloid opiates and thus may form the basis for an unified receptor site model. It has been shown furthermore that peptides containing the Tyr-Tic motif , as TIPP, act as very selective antagonists for δ-opioid receptors and those containing Tyr-D-Tic as non-selective μ-agonists.
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