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Product details
Cat#:186P36
Three Letter Code: H-Leu-Val-Val-Tyr-Pro-Trp-Thr-Gln-Arg-OH
One Letter Code: LVVYPWTQR
Synonyms: LVV-Hemorphin-6 (human), Spinorphin-Gln-Arg
Molecular Formula: C₅₆H₈₄N₁₄O₁₃
Relative Molecular Mass: 1161.37
CAS#: 135861-77-7
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Opioid Research
Details: Leu-Valorphin-Arg, LVVYPWTQR, corresponds to the sequence (32-40) of the β-,δ-,γ-, and ε-chains of human hemoglobin. It shows binding affinity for µ- and sigma-opioid receptors and has opioid activity in the GPI bioassay. LVV-Hemorphin-6 is found in large amounts in the pituitary and seems to be present in the circulation to a much lesser degree. In view of its high stability towards the membrane-bound lung enzymes and its strong inhibitory action on ACE activity, LVV-hemorphin-6 appears to be the most potent of the hemorphin-related peptides assayed.
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