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Product details
Cat#：191P04
Three Letter Code: β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Orn-Gly-NH₂ trifluoroacetate salt(Disulfide bond)
One Letter Code: β-Mercapto-β,β-cyclopentamethylene-propionyl-Y(Me)-IQNCP-Orn-G-NH₂(Disulfide bond)
Synonyms: [Pmp1, Tyr(OMe)2, Orn8] Vasotocin
Molecular Formula: C₄₈H₇₄N₁₂O₁₂S₂
Relative Molecular Mass: 1075.32
CAS#: 77327-45-8
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Pituitary & Hypothalamic Hormones
Details: Potent oxytocin antagonist with a pA₂ value of 7.35 ± 0.08. (d(CH₂)₅¹,Tyr(Me)²,Orn⁸)-Vasotocin has been used to support the hypothesis that pituitary secretion of oxytocin is associated with coactivation of centrally projecting brain oxytocin pathways, some of which are causally related to the induced inhibition of food intake. Furthermore, this compound competitively inhibited arginine vasotocin (AVT) contractions without affecting AVT efficacy.
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