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Product details
Cat#：194P32
Three Letter Code: H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH trifluoroacetate salt
One Letter Code: SFLLRNPNDKYEPF
Synonyms: Thrombin Receptor Activator Peptide 14, PAR-1 (1-14) (human), Proteinase Activated Receptor 1 (1-14) (human), Thrombin Receptor (1-14) (human), Coagulation Factor II Receptor (1-14) (human), Thrombin Related Peptide
Molecular Formula: C₈₁H₁₁₈N₂₀O₂₃
Relative Molecular Mass: 1739.95
CAS#: 137339-65-2
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cardiovascular System & Diseases|
Hematology
Details: Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation.
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