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Product details
Cat#：194P33
Three Letter Code: H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-NH₂ trifluoroacetate salt
One Letter Code: SFLLRNPNDKYEPF-NH₂
Synonyms: Thrombin Receptor Activator Peptide 14 amide, Proteinase Activated Receptor 1 (1-14) amide (human), PAR-1 (1-14) amide (human), Thrombin Receptor (1-14) amide (human), Coagulation Factor II Receptor (1-14) amide (human)
Molecular Formula: C₈₁H₁₁₉N₂₁O₂₂
Relative Molecular Mass: 1738.96
CAS#: 141923-36-6
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Hematology|
Nitric Oxide Research
Details: TRAP-14 amide, SFLLRNPNDKYEPF-NH2, has been shown to inhibit monocyte spreading on fibronectin-coated slides. The rapidly induced withdrawal of pseudopodial processes and rounding of the cells is accompanied by nitric oxide and endothelin-1 release. Spreading might be inhibited by autocrine endothelin-1 release and subsequent endothelin B receptor-dependent nitric oxide production.
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