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/Renin Inhibitors and Substrates (16)
/H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Ser-OH trifluoroacetate salt
Product details
Cat#:201P07
Three Letter Code: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Ser-OH trifluoroacetate salt
One Letter Code: DRVYIHPFHLVIHS
Synonyms: (Ser¹⁴)-Angiotensinogen (1-14) (human), (Ser¹⁴)-Preangiotensinogen (1-14) (human), (Ser¹⁴)-Tetradecapeptide Renin Substrate (human)
Molecular Formula: C₈₂H₁₂₁N₂₃O₁₉
Relative Molecular Mass: 1733.01
CAS#: 91999-74-5
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cardiovascular System & Diseases
Details: The tetradecapeptide DRVYIHPFHLVIHS is an excellent substrate for human kidney renin (Km = 8.4 +/- 2.9 µM, pH 7.2, 37 °C). Human liver cathepsin D, rabbit lung angiotensinogen-converting enzyme, and reconstituted human serum also show slight abilities to cleave this substrate but do not produce detectable amounts of angiotensin I.
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