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Product details
Cat#：203P16
Three Letter Code: 3,5-Difluorophenylacetyl-Ala-Phg-OMe
One Letter Code: 3,5-Difluorophenylacetyl-A-Phg-OMe
Synonyms: DAPM
Molecular Formula: C₂₀H₂₀F₂N₂O₄
Relative Molecular Mass: 390.39
CAS#: 208255-51-0
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Alzheimer´s Disease
Details: DAPM, a cell-permeable γ-secretase inhibitor with anti-aggregation properties that dose-dependently inhibits amyloid β-protein (Aβ) secretion in 7PA2 Chinese hamster ovary (CHO) cells with an half-maximal inhibitory concentration of IC₅₀ ~ 10 nM. DAPM prevents oligomer formation by selectively blocking the Aβ dimer and trimer formation at doses that allow appreciable monomer production.
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2）Provide us peptides information including Sequence, Purity, Quantity and modification(If necessary, we agree to sign confidential agreement with you before you provide these information), we will make you a quotes within 30 minutes;
3）Place us a purchaser order, we can send you a sales contract too if you need;
4）Start synthesis, and we will inform you the updates of synthesis in time;
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6）Refund all pre-payment(if pre-pay us) if we failed to synthesize any of them.
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