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Product details
Cat#:203P19
Three Letter Code: N-Me-Abz-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH₂ trifluoroacetate salt
One Letter Code: N-Me-Abz-GGVVIATVK(Dnp)rrr-NH₂
Synonyms: N-Me-Abz-APP₇₇₀ (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide, N-Me-Abz-Amyloid β-Protein (37-44)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide
Molecular Formula: C₇₀H₁₁₆N₂₆O₁₈
Relative Molecular Mass: 1609.86
CAS#: 600728-90-3
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Alzheimer´s Disease
Details: Intramolecularly quenched fluorescent, presenilin-dependent substrate for assaying γ-secretase activity. The FRET substrate has been used for partial purification and characterization of γ-secretase from post-mortem human brain.
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