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Product details
Cat#：203P22
Three Letter Code: Z-Leu-Leu-4,5-dehydro-Leu-aldehyde
One Letter Code: Z-LL-4,5-dehydro-L-aldehyde
Synonyms: SIB 1281, Z-Leu-Leu-4,5-dehydro-Leu-CHO
Molecular Formula: C₂₆H₃₉N₃O₅
Relative Molecular Mass: 473.61
CAS#: 181139-85-5
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Alzheimer´s Disease
Details: The peptide aldehyde SIB1281 inhibited the formation of β- and γ-secretase derived amyloid β-protein (Aβ) with IC₅₀ = 1.8 µM and stimulated the formation of α-secretase derived soluble amyloid precursor protein (sα) with an EC₅₀ of 250 nM.
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