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Product details
Cat#：210P02
Three Letter Code: Pyr-His-Pro-NH₂
One Letter Code: pEHP-NH₂
Synonyms: Thyroliberin, Prolactoliberin, Prolactostatin, Protirelin, Thyrotropin-Releasing Hormone
Molecular Formula: C₁₆H₂₂N₆O₄
Relative Molecular Mass: 362.39
CAS#: 24305-27-9
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Di- and Tripeptides|
Diabetes|
Obesity Research|
Veterinary Medicine
Details: TRH exhibits a variety of biological effects, when injected into humans or animals. Its physiological role appears to be the stimulation of thyrotropin (TSH) and prolactin (PRL) release from the anterior pituitary. Though it was first identified in the hypothalamus as a regulator of the pituitary-thyroid axis, TRH was detected as well by Luo et al. in pancreatic β-cells co-localized with insulin. Application of the hormone reverted hyperglycemia in rats. Moreover, TRH plays an important role in the control of human hair-growth and hair follicle pigmentation.
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