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Product details
Cat#：215P21
Three Letter Code: H-Lys-Pro-Arg-Arg-Pro-Tyr-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂
One Letter Code: KPRRPYTDNYTRLRKQMAVKKYLNSILN-NH₂
Synonyms: [Lys1, Pro2,5, Arg3,4, Tyr6] VIP, human, porcine, rat, ovine
Molecular Formula: C₁₅₄H₂₅₇N₄₉O₄₀S
Relative Molecular Mass: 3467.11
CAS#: 125093-93-8
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cancer Research
Details: VIP antagonist, a hybrid of neurotensin (6-11) and VIP (7-28), is a competitive antagonist of VIP-binding to glial cells. In rats with reduced masculine potential, The peptide markedly inhibits VIP-stimulated sexual behaviour. Furthermore, it has been shown to antagonize VIP receptors on non-small cell lung cancer cells, thereby inhibiting tumor growth in vitro and in vivo.
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