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Product details
Cat#: 107P138
Three Letter Code: H-Lys-Glu-Gly-Val-Val-His-Gly-Val-Ala-Thr-OH
One Letter Code: KEGVVHGVAT
Molecular Formula: C₄₃H₇₃N₁₃O₁₄
Relative Molecular Mass: 996.12
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Areas of Interest: Alzheimer´s Disease
Parkinson’s Disease
Details: Aggregation of α-synuclein (α-syn) into toxic fibrils is a pathogenic hallmark of Parkinson’s disease (PD). Most early onset mutations are located between residues 46-53. The sequence of α-synuclein (45-54) was used by Cheruvara and coworkers as a template for a peptide library. The authors isolated a 10-residue peptide antagonist that potently inhibits α-synuclein aggregation and associated toxicity at 1:1 stoichiometry.
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