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Product details
Cat#: 107P142
Three Letter Code: Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH₂
One Letter Code: Ac-KDGIVNGVKA-NH₂
Molecular Formula: C₄₅H₈₀N₁₄O₁₄
Relative Molecular Mass: 1041.2
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Areas of Interest: Alzheimer´s Disease
Parkinson’s Disease
Details: Cheruvara and coworkers conducted a single step selection followed by two rounds of competition selection protein-fragment complementation assay (PCA) in order to derive α-synuclein (α-syn) binders capable of inhibiting aggregation. They isolated a 10-residue peptide antagonist, corresponding to the sequence of α-synuclein binding peptide that potently inhibits α-synuclein aggregation and associated toxicity at 1:1 stoichiometry.
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