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Product details
Cat#: 109P11
Three Letter Code: H-Val-Tyr-Thr-Val-Gln-Ile-Cys-Thr-Lys-Ser-Gly-Asp-Trp-Lys-Ser-Lys-Cys-Phe-Tyr-Thr-Thr-OH (Disulfide bond)
One Letter Code: VYTVQICTKSGDWKSKCFYTT
Molecular Formula: C₁₁₁H₁₆₆N₂₆O₃₃S₂
Relative Molecular Mass: 2456.83
CAS#: 313642-01-2
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Areas of Interest: Cardiovascular System & Diseases
Hematology
Details: Tissue factor (TF) is a transmembrane protein that functions as a cofactor for the serine protease factor VIIa in the initiation of blood coagulation in vivo. The 21-mer VYTVQICTKSGDWKSKCFYTT is a specific inhibitor of TF-dependent clotting. With an 11-membered disulfide-bridged ring it displayed a 4-fold enhancement of potency compared to the linear TF residue.
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