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Product details
Cat#: 114P02
Three Letter Code: H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
One Letter Code: QRPRLSHKGPMPF
Molecular Formula: C₆₉H₁₁₁N₂₃O₁₆S
Relative Molecular Mass: 1550.85
CAS#: 217082-58-1
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Areas of Interest: Obesity Research
Details: Apelin-13, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC₅₀) value of 0.37 nM. In a study of Valle et al. chronic central administration of apelin-13 over 10 days increased food intake, body weight, locomotor activity and body temperature in C57BL/6 mice.
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