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Product details
Cat#: 120P22
Three Letter Code: H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH₂
One Letter Code: VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH₂
Synonyms: Calcitonin Gene-Related Peptide I (8-37) (mouse, rat), CGRP-I (8-37) (mouse, rat)
Molecular Formula: C₁₃₈H₂₂₄N₄₂O₄₁
Relative Molecular Mass: 3127.56
CAS#: 129121-73-9
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Details: α-CGRP (8-37), a competitive CGRP1 receptor antagonist, exhibited hypothermic and antinociceptive effects. CGRP-I (8-37) antagonized the effects of amylin and amylin (1-8) on osteoblasts but was substantially less potent in this regard than amylin (8-37). Furthermore, it inhibited the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats.
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