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Product details
Cat#：130P11
Three Letter Code: H-Phe-Lys-Ala-β-cyclohexyl-Ala-β-cyclohexyl-Ala-Leu-D-Ala-Arg-OH
One Letter Code: FKA-β-cyclohexyl-Ala-β-cyclohexyl-Ala-LaR
Molecular Formula: C₅₁H₈₆N₁₂O₉
Relative Molecular Mass: 1011.32
CAS#: 133214-60-5
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Inflammation Research
Details: The C5a-related octapeptide Phe-Lys-Ala-Cha-Cha-Leu-D-Ala-Arg possesses a high binding affinity for polymorphonuclear leukocyte membranes (Ki = 0.09 µM). It has therefore been used as a leading analog for the development of specific C5a antagonists, which are of considerable therapeutic interest for the treatment of inflammatory disorders and tissue damage.
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