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Product details
Cat#: 101P03
Three Letter Code: Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH
One Letter Code: Ac-AMVSEFLKQAWFIENEEQEYVQTVK
Synonyms: Annexin-1 (2-26) (human), Lipocortin-1 (2-26), Calpactin II (1-25) (dephosphorylated) (human), Ac2-26
Molecular Formula: C₁₄₁H₂₁₀N₃₂O₄₄S
Relative Molecular Mass: 3089.47
CAS#: 151988-33-9
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Areas of Interest: Cancer Research
Cardiovascular System & Diseases
Inflammation Research
Details: Annexin A1 (AnxA1) N-terminal-derived peptide, also known as Ac2-26, mimics the antiinflammatory effects of AnxA1. Ac2-26 can activate all three formyl peptide receptor family members FPR, FPR-like (FPRL)1 and FPRL2 at similar concentations. It represents the first endogenous ligand for FPRL2. In myocardial ischemia-reperfusion injury experiments the peptide showed cardioprotective effects. Understanding the underlying mechanism may help developing novel therapeutics for acute cardioprotection.
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