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Product details
Cat#：132P10
Three Letter Code: Ac-tBu-Gly-tBu-Gly-Asn(Me)₂-Ala-AMC
Synonyms: Ac-Tle-Tle-Asn(Me)₂-Ala-AMC
Molecular Formula: C₃₃H₅₀N₆O₈
Relative Molecular Mass: 658.79
CAS#: 204909-38-6
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Virology
Details: Ac-Tle-Tle-Asn(Me)₂-Ala-AMC is the shortest human cytomegalovirus (HCMV) protease substrate to date. It displayed excellent kinetic properties with kcat and Km values of 0.035 s⁻¹ and 13.2 µM, respectively. The resultant specificity constant kcat/Km of 2650 M⁻¹ s⁻¹ was 10-fold greater than for the non-improved substrate Abz-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-3-nitro-Tyr-Arg-OH.
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