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Product details
Cat#:132P13
Three Letter Code: DABCYL-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-EDANS trifluoroacetate salt
One Letter Code: DABCYL- RGVVNASSRLA -EDANS
Molecular Formula: C₇₃H₁₀₉N₂₃O₁₈S
Relative Molecular Mass: 1628.88
CAS#: 163265-38-1
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Virology
Details: The FRET substrate Dabcyl-RGVVNASSRLA-Edans has been synthesized to develop a fluorescence-based assay of human cytomegalovirus proteinase. It is cleaved specifically at the Ala-Ser bond thereby liberating the C-terminal peptide-EDANS fragment from the proximity quenching effect of the DABCYL group. This represents the first fluorescence-based assay of the herpes virus proteases and permits the characterization of potential inhibitors.
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