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Product details
Cat#: 101P06
Three Letter Code: H-Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg-OH
One Letter Code: VCYDKSFPISHVR
Synonyms: Connexin 43 (63-75) (human, bovine, mouse, rat), Gap Junction α-1 Protein (63-75)
Molecular Formula: C₇₀H₁₀₇N₁₉O₁₉S
Relative Molecular Mass: 1550.78
CAS#: 197250-15-0
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Details: GAP26 corresponds to residues 63-75 of connexin 43, a gap junction-blocking transmembrane protein. GAP26 attenuates the rhythmic contractile activity of rabbit arterial smooth muscle (IC₅₀ 28.4 mM). The peptide also inhibits IP3-induced ATP release without inhibiting gap junctional coupling in endothelial cells.
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