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/Dynorphin, Analogs and Sequences (38)
/Acetyl-(D-Lys²,Sar³)-Melanotropin-Potentiating Factor acetate salt
Product details
Cat#：136P35
Three Letter Code: Ac-Lys-D-Lys-Sar-Glu-OH acetate salt
One Letter Code: Ac-Kk-Sar-E
Synonyms: Acetyl-(D-Lys⁸⁹,Sar⁹⁰)-β-Lipotropin (88-91) (human), Acetyl-(D-Lys²⁹,Sar³⁰)-β-Endorphin (28-31) (human)
Molecular Formula: C₂₂H₄₀N₆O₈
Relative Molecular Mass: 516.6
CAS#: 81483-91-2
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Parkinson’s Disease
Details: This metabolically stable analog of MPF is known as a neurotrophic peptide capable of CNS regeneration. It has been shown to reduce parkinsonian-like behaviour in rats with unilateral lesions of their nigro-striatal pathways. This effect is related to reversal of the mitochondrial damage to the neurons. As a mitochondrial defect is supposed to be the initial step in the genesis of Parkinson´s disease, the peptide may be a very useful tool in the investigation of this disease.
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