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Product details
Cat#: 101P09
Three Letter Code: H-Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH₂
One Letter Code: LRAHAVDVNG-NH₂
Synonyms: Cadherin-1 (76-85) amide (chicken), N-Cadherin (76-85) amide (chicken), Cadherin Peptide, avian
Molecular Formula: C₄₄H₇₅N₁₇O₁₃
Relative Molecular Mass: 1050.19
CAS#: 127650-08-2
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Areas of Interest: Adhesion Molecules & Extracellular Matrix Proteins
Cell Culture
Regenerative Medicine
Details: This decapeptide resides within the first extracellular domain (EC1) of N-cadherin. It inhibits cadherin-mediated cell adhesion, compaction of eight-cell-stage mouse embryos and rat neurite outgrowth on astrocytes. In the presence of this peptide Ca²⁺-dependent cell aggregation of bovine brain microvessel endothelial cells is prevented. A putative application in creating channels for paracellular drug delivery across blood brain barriers has been proposed.
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