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Product details
Cat#:137P24
Three Letter Code: Ac-D-Trp-Leu-Asp-Ile-Ile-Trp-OH
One Letter Code: Ac-wLDIIW
Synonyms: Ac-[DTrp16] Endothelin-1 (16-21), human
Molecular Formula: C₄₆H₆₂N₈O₁₀
Relative Molecular Mass: 887.05
CAS#: 143037-33-6
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Cardiovascular System & Diseases
Details: Displays high affinity for the ET-A receptor (IC₅₀ = 0.13 µM) and inhibits the ET-1 stimulated arachidonic acid release in rabbit vascular smooth muscle cells. The hexapeptide binds specifically to the pituitary GnRH receptor exhibiting agonistic activity.
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