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Product details
Cat#: 101P12
Three Letter Code: H-Pro-Gly-Pro-OH
One Letter Code: PGP
Molecular Formula: C₁₂H₁₉N₃O₄
Relative Molecular Mass: 269.3
CAS#: 7561-51-5
Source: Synthetic
Storage Conditions: -20 ± 5 °C, avoid light, cool and dry place
Areas of Interest: Adhesion Molecules & Extracellular Matrix Proteins
Di- and Tripeptides
Regenerative Medicine
Details: H-Pro-Gly-Pro-OH (PGP) is a tripeptide generated from the breakdown of extracellular matrix collagen and is specifically chemotactic for neutrophils in vitro and in vivo. N-terminal acetylation of PGP (AcPGP - Bachem product H-6412) can enhance this chemotactic potential. PGP was identified as physiological substrate for the aminopeptidase activity of leukotriene A4 hydrolase. PGP is a biomarker for chronic obstructive pulmonary disease (COPD).
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