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Product details
Cat#：195P06
Three Letter Code: H-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH₂ trifluoroacetate salt
One Letter Code: IKPEAPGEDASPEELNRYYASLRHYLNLVTRQRY-NH₂
Synonyms: PYY (3-36) (human)
Molecular Formula: C₁₈₀H₂₇₉N₅₃O₅₄
Relative Molecular Mass: 4049.52
CAS#: 123583-37-9
Source: Synthetic
Storage Conditions: -20 ± 5 °C
Areas of Interest: Gastrointestinal Research|
Obesity Research
Details: PYY (3-36), a Y2 receptor agonist, is released from the body´s gastrointestinal tract in proportion to caloric intake. It has been shown that peripheral injection of PYY (3-36) in rats inhibited food intake and reduced weight gain. In addition, infusion of PYY (3-36) in humans significantly decreased appetite and reduced food intake by 33% over 24h, which suggests that PYY (3-36) has a role in ´longer term´ regulation of food intake. Thus, the PYY (3-36) may represent a lead compound for the development of drugs for the treatment of obesity.
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